CAS No.: | 9003-39-8 | Appearance: | White Powder |
---|---|---|---|
Molecular Weight: | 45,000-58,000 | Molecular Formula: | (C6H9NO)n |
PH: | 3-5 | K-value: | 27-32 |
Highlight: | 9003-39-8 Pharmaceutical Excipient,Povidone PVP K30,pvp k30 and pvp k90 |
New And Excellent Pharmaceutical Excipient Polyvinylpyrrolidone (PVP)
Chemical Name: Polyvinylpyrrolidone (PVP)
CAS No: 9003-39-8
Properties:
Nontoxic; non-irritant; hygroscopic; Freely soluble in water , excellent solubility; film-forming; Chemical stability; physiologically inert; complexation and binding property
Specifications
Based on the polymer molecular weight and viscosity in water, the current series products are classified based on their K-Values
Product | K-value | M.W | Main Application |
K12 | 10.2-13.8 | 3,000-7,000 | Used as s solubilizer,dispersant and anti-crystallization agent in liquid dosage applications |
K15 | 12.75-17.25 | 8,000-12,000 | |
K17 | 15.3-18.36 | 10,000-16,000 | |
K25 | 22.5-27.0 | 30,000-40,000 | Used as a binder, film–forming agent, solubilizer, suspension stabilizer and dispersant in dosage form applications |
K30 | 27-32.4 | 45,000-58,000 | |
K60 | 54-64.8 | 270,000-400,000 | Used as a binder, thickener or suspension stabilizer in dosage form applications |
K90 | 81-97.2 | 1,000,000-1,500,000 |
Application
Povidone K series products posses excellent binding, film-forming, dispersing and thickening properties and are widely used in the following dosage forms:
Binder: Suitable for wet and dry granulation and direct compression in tableting, improves particle compressibility
Solubilizer: suitable for oral and parenteral formulations, enhancing the solubility of poorly soluble drugs in solid dispersion forms.
Coating agent or binder: coating of active pharmaceutical ingredients on a support, such as sugar beads, suspending
Stabilizing or viscosity-modifying agent: suitable for topical and oral suspension and solution applications.
Combined with povidone, the solubility of poorly soluble drugs may be enhanced.
Packing
Packed in 25kg/fiber drum.