K Value: | 10.2-13.8 | Water: | 5.0% Max |
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PH: | 3.0-5.0 | Appearance: | White Powder |
Highlight: | Solubilizer Povidone K12,Pharmaceutical Povidone K12 Powder,Polyvinylpyrrolidone PVP K12 Powder |
New Pharmaceutical Excipients Povidone K12 High Quality PVP K12
Properties:
Nontoxic; non-irritant; hygroscopic; Freely soluble in water , alcohol and most other organic solvents; excellent solubility; film-forming; Chemical stability; physiologically inert; complexation and binding property
Specifications
Based on the polymer molecular weight and viscosity in water, the current series products are classified based on their K-Values
Product | K-value | M.W | Main Application |
K12 | 10.2-13.8 | 3,000-7,000 | Used as s solubilizer,dispersant and anti-crystallization agent in liquid dosage applications |
K15 | 12.75-17.25 | 8,000-12,000 | |
K17 | 15.3-18.36 | 10,000-16,000 | |
K25 | 22.5-27.0 | 30,000-40,000 | Used as a binder, film–forming agent, solubilizer,suspension stabilizer and dispersant in dosage form applications |
K30 | 27-32.4 | 45,000-58,000 | |
K60 | 54-64.8 | 270,000-400,000 | Used as a binder, thickener or suspension stabilizer in dosage form applications |
K90 | 81-97.2 | 1,000,000-1,500,000 |
Application
Povidone K series products posses excellent binding, film-forming, dispersing and thickening properties and are widely used in the following dosage forms:
Binder: Suitable for wet and dry granulation and direct compression in tableting, improves particle compressibility and can be added to powder blends in dry or granulated forms by the addition of water, alcohol or hydro-alcoholic solutions.
Solubilizer: suitable for oral and parenteral formulations, enhancing the solubility of poorly soluble drugs in solid dispersion forms.
Coating agent or binder: coating of active pharmaceutical ingredients on a support, such as sugar beads, suspending
Stabilizing or viscosity-modifying agent: suitable for topical and oral suspension and solution applications.
Combined with povidone, the solubility of poorly soluble drugs may be enhanced.
Packing
Packed in 25kg/fiber drum.